COMPARATIVE ANALYSIS OF THE OUTCOMES OF CONTINUOUS AND BOLUS ADMINISTRATION OF SEDATIVES IN CHILDREN UNDERGOING MECHANICAL VENTILATION

Received: 2025-05-06

Published: 2025-05-03

Abstract

Adequate sedation is an essential component of the management of children on mechanical ventilation. The optimal regimen of sedation remains a matter of debate. Continuous infusion ensures a stable concentration of the drug in the blood and can reduce the risk of desynchronization with the respirator, however, it is associated with the development of tolerance and withdrawal syndrome. Bolus administration reduces the cumulative dose of drugs, but may be accompanied by periodic discomfort and anxiety of the patient.

List of references

About the Authors

Alimov A.A.
Children's National Medical Center
Usmanov R.R.
Children's National Medical Center
Usmanov J.R.
Children's National Medical Center
Tukhtasinov T.M.
Children's National Medical Center
Rasulov A.A.
Children's National Medical Center
Arslanov Kh.S.
Children's National Medical Center
Satvaldieva E.A.
Children's National Medical Center
Abdullayeva M.S.
Children's National Medical Center
Mavlyankhodzhaev Z.S.
Children's National Medical Center

How to Cite

COMPARATIVE ANALYSIS OF THE OUTCOMES OF CONTINUOUS AND BOLUS ADMINISTRATION OF SEDATIVES IN CHILDREN UNDERGOING MECHANICAL VENTILATION. (2025). Herald of the National Children’s Medical Center, 13-14. https://hnchmc.uz/jour/article/view/95

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