CLINICAL ASPECTS OF KIDNEY TRANSPLANTATION IN CHILDREN FROM THE POSITION OF AN ANESTHESIOLOGIST-RESUSCITATOR
Abstract
Kidney transplantation is a high-tech radical method of renal replacement therapy that can signiKcantly prolongs
the life and imrove its quality in patients with end-stage chronic renal failure (CRF). In pediatric patients, a successfully performed kidney transplantion not only eliminates the clinical manifestations of chronic renal failure, but also normalizes bone
growth, puberty, mental development and social adaptation.
About the Authors
List of references
Shumakov V.I. Transplantologiya [Transplantology] 2nd edition, MIA., 2006, 504 p.
Stolyar A.G., Budkar L.N., Klimusheva N.F., Lesnyak O.M. Uluchsheniye resultatov transplantatsii pochki [Improving the results of kidney transplantation.]. Vestnik transplantologii I iskustvennih organov - Bulletin of transplantology and artificial organs., 2014, no.4, pp.55-61 doi.org/10.15825/1995-1191-2014-4-55-61
Kolsanov A.V., Limareva L.V., Danilchenko O.P., Popova S.I. Sovremenniye tehnologii v immunologicheskom obespechenii transplantatsii [Modern technologies in immunological support of kidney transplantation]. Meditsinskiy almanah - Medical Almanac, 2008, May, pp. 51-52.
Lazarev V.V., Tsypin L.E., Kochkin V.S., Valov A.L., Ektov D.B. Gemodinamika pri obshey anestezii s epiduralnoy I bez epiduralnoy blokadi vo vremya transplantatsii pochki u detey [Hemodynamics under general anesthesia with and without epidural blockade during kidney transplantation in children]. Anesteziologiya I reanimatologiya - Anesthesiology and Reanimatology 2013, no.1, pp. 42-44.
S. A. Hebert , R.D.Swinford , D.R.Hall , J.K.Au, J.S.B ynon. Special Considerations in Pediatric Kidney Transplantation.Adv Chronic Kidney Dis., 2017, Nov., 24(6)., pp. 398-404. doi: 10.1053 / j.ackd. 2017.09.009.
P.S.Verghese. Pediatric kidney transplantation: a historical review.Pediatr Res. 2017 Jan;81(1-2):259-264. doi: 10.1038/pr.2016.207
Ключевыми требованиями являются продолжение иммуносупрессивной терапии и мониторинг признаков раннего отторжения трансплантанта.
Имуносупрессорная терапия (ИСТ) остаётся клю¬чевым звеном в лечении реципиентов почки и непо¬средственно влияет на развитие послеоперационных осложнений, продолжительность функционирования трансплантанта, отдалённую выживаемость и качество жизни пациентов с терминальной стадией ХПН (ХБП IV- V стадии) [10, 25, 26].
Иммунная система у детей требует более диф¬ференцированного применения иммуносупрессивных средств, чем у взрослых. Тяжесть побочных эффектов сте¬роидов в условиях растущего организма свидетельствует о необходимости осторожного подхода к их проведению.
Carolina Cordinha , Luis Rodrigues , Carmen Carmo , Clara Gomes , Fernando Macario, A Jorge Correia , Rui Alves , Arnaldo Figueiredo. Pediatric Kidney Transplantation: Experience of a Center Over 4 Decades. Transplant Proc. 2019,Jun;51(5),pp.1579-1584. doi: 10.1016 / j.transproceed.2019.05.007.
Giessing M., Muller D., Winkelmann B.et al. Kidney transplantation in children and adolescents. Transplantant. Proc. 2007, pp. 552-558
Coupe N., O'Brien M., Gibson P., De Lima J., Anesthesia for pediatric renal transplantation with and without epidural analgesia - a review of 7 years' experience., Pediatr. Anesth., 2005, Vol. 15. pp. 220-228
National general clinical recommendations of the All-Russian public organization of transplantologists "Russian Transplant Society”. Kidney transplantation. 2013
Odeh R.I., Sidler M. , Skelton T., Zu'bi F. , Naoum N.K. , Azzawayed I., Alyami F.A., Lorenzo A.J., Farhat W.A., Koyle M.A. Intraoperative blood transfusion in pediatric patients undergoing renal transplant. Effect of renal graft size. Pediatr Transplant. -2018. -Vol. 22. -№3. -P. e13119. doi: 10.1111/petr.13119.
Urquijo I.A., Goni M.H., Garcia G.O., Menica M.A. Pediatric renal transplantation in children with weight 20kg or less. International Journal of Anesthesiology & Research (IJAR). January 2019, pp.555-564 doi:10.19070/2332-2780- 19000112
Gabriel M. Danovich M.D.. Handbook of kidney transplantation.5th.ed. LWW,2009, (Russ. ed.: Moyasuk Ya.G. Transplantatsiya pochki Moscow, GEOTAR-Media, 2014, 656-722 p.
Khubutia M.Sh., Magilevets V.M. Anestesiya pri transplantatsii donorskoy pochki. [Anesthesia during donor kidney transplantation]. Moscow, 2019 pp.
Keye АЯ, Fox Ch.J., Diaz J.H. Essentials of Pediatric Anesthesiology USA, 2014, (Russ. ed.: Pediatric anesthesiologychapter 33, pp.625-632.
Odeh R.I., Sidler M., Skelton T., et al. Intraoperative blood transfusion in pediatric patients undergoing renal transplant. Effect of renal graft size. Рediatric transplantology. -2018. -№. 3 pp 243-245
GiessingM., Muller D., Winkelmann B., Roigas J., Loening
S.A. Kidneytransplantation in children and adolescents. Transplant. Proced.,2007 Sep;39(7):2 pp.197-201
Heurn E.V., Vries E.E. Kidney transplantation and donation in children. Pediatr. Surg. Int.2009 may; 25 (5), pp. 385-393.
Chandar J. , Chen L., Defreitas M., Ciancio G. , George Burke G.Donor considerations in pediatric kidney transplantation.,Pediatr. Nefrol.2021 Feb;36(2), pp.245¬257.
Rocca G.D. , Costa M.G., Bruno K., Coccia C., L Pompei L., Marco P.D., Pretagostini R., Colonnello M., Rossi M., P Pietropaoli P., Cortesini R.Anesthetic management ofkidney transplantation in children. Pediatr Surg. Int.2001. Mar;17(2-3), pp.175-179.
Otukesh H., Hoseini R., Rahimzadeh N., et al. Outcome of renal transplantation in children: a multi-center national report from Iran. Pediatr. Transpl. 2011 Vol. 15. №5, pp.533-538
Conzen P.F., Kharasch E.D., Czerner S.F., et al. Low- flow sevoflurane compared with low-flow isoflurane anesthesia in patients with stable renal insufficiency. Anesthesiology, 2002, Vol. 97. №5 pp. 578-584
Sear J.W. Anesthesia for patients undergoing renal transplantation. In kidney transplantation. Principles and practice. Fifth edition, Morris J. Philadelphia, W.B Saunders, 2001, pp.184-207
Kang Y. Anesthetic management in kidney transplantation.Renal Transplantation. Ed. Ron Shapiro, Appletion & Lange, 1997, pp. 97-101.
Fadel F.I., Bazaraa H.M., Badawy H., et al. Pediatric kidney transplantation in Egypt: Results of 10-year single-center experience.Pediatr Transplant. -2020. -№6. -P. 13724. doi: 10.1111/petr.13724
Winterberg P.D.,Garro R. Long-Term Outcomes of Kidney Transplantation in Children.Pediatr Clin North Am. -2019 -Vol.66-№1, -P.269-280. doi: 10.1016/j.pcl.2018.09.008
Voet M., Nusmeier A., Lerou J., et al. Cardiac output- guided hemodynamic therapy for adult living donor kidney transplantation in children under 20 kg: A pilot study.Paediatr Anaesth. 2019 Sep;29(9),pp.950-958. doi: 10.1111/pan.13705. Epub 2019 Aug 4
Yanaral T.U., Karaaslan P. Evaluation of the learning curve of pediatric kidney transplantation anesthesia. Turk J Med Sci. -2021. -Vol. 51-№3. -P. 1234-1239. doi: 10.3906/ sag-2012-291
Taylor K., Kim W.T., Maharramova M., et al. Intraoperative management and early postoperative outcomes of pediatric renal transplants.Paediatr Anaesth. -2016. -Vol. 26(10). -P. 987-91. Epub 2016 Aug 18. doi: 10.1111/pan.12979