Faqat arterial kirish yo‘li orqali tana vazni 10 kg dan kam bo‘lgan chaqaloqlarda qorinchaaroq to‘siq nuqsonini transkateter usulida yopish: bitta markaz tajribasi
Referat
Maqsad. 10 kg dan kam vaznga ega chaqaloqlarda qorinchalararo to‘siq nuqsonini (VSD) transkateter usulida yopish kichik bemor o‘lchamlari, qon tomir kirish yo‘llarining cheklanganligi va asoratlar xavfining yuqoriligi sababli texnik jihatdan murakkab hisoblanadi. Faqat arterial kirish yo‘li usuli jarayonni soddalashtirish orqali afzalliklar berishi mumkin. Ushbu tadqiqot 10 kg dan kam vaznga ega chaqaloqlarda faqat arterial kirish yo‘li orqali VSD ni transkateter yopishning xavfsizligi, samaradorligi va o‘rta muddatli natijalarini baholaydi.
Materiallar va usullar. O‘rtacha yoshi 14,5 oy (IQR 10–21,5) va o‘rtacha vazni 8,95 kg (IQR 8–9) bo‘lgan 20 chaqaloqqa (9 o‘g‘il bola [45%], 11 qiz bola [55%]) faqat arterial kirish yo‘li orqali VSD transkateter yopilishi amalga oshirildi. O‘rtacha nuqson o‘lchami 4,5 mm (IQR 3,5–4,95), qurilma diametri esa 7×5 dan 8×6 mm gacha (o‘rtacha 7×5) bo‘ldi. O‘rtacha ftoroskopiya dozasi 19 mGr (IQR 13–29,5), jarrohlik jarayoni o‘rtacha 50 daqiqa (IQR 40–60) davom etdi. Kuzatuv muddati o‘rtacha 15 oy (IQR 12–22) bo‘ldi.
Natijalar. Jarayon 100% muvaffaqiyatli yakunlandi. 1 yil ichida 15% bemorda qoldiq shunt kuzatildi. 30% bemorda trikuspital regurgitatsiya qayd etildi, aortal regurgitatsiya holati aniqlanmadi. Jiddiy asoratlar yoki o‘lim holatlari qayd etilmadi.
Xulosa. 10 kg dan kam vaznga ega chaqaloqlarda faqat arterial kirish yo‘li orqali VSD transkateter yopilishi amalga oshirilishi mumkin va xavfsiz bo‘lib, o‘rta muddatli ijobiy natijalarni beradi. Ushbu usul jarayon vaqtini va kontrast moddaga tushadigan yukni kamaytirishi mumkin, bu esa uni kichik chaqaloqlar uchun jozibador variantga aylantiradi.
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Adabiyotlar ro'yxati
Zhang Y, et al. Logistic regression analysis of factors associated with left ventricular cavity normalization after interventional VSD closure. *Front Cardiovasc Med*. 2023;10:1255808. https://doi.org/10.3389/ fcvm.2023.1255808.
Wang J, et al. Outcomes of transcatheter ventricular septal defect closure in infants: a multicenter study.
*Pediatr Cardiol*. 2023. https://doi.org/10.1007/s00246-023-03350-3.
Kumar S, et al. Safety and efficacy of device closure of perimembranous ventricular septal defects in infants weighing less than 10 kg. *Pediatr Cardiol*. 2025. https://doi.org/10.1007/s00246-025-03782-z.
Saito K, et al. Current status and future perspectives of transcatheter ventricular septal defect closure in infants and children. *Circ J*. 2023;88(5):CJ-23-0891. https://doi.org/10.1253/circj.CJ-23-0891.
Kamran MM. Transcatheter closure of ventricular septal defects: a comprehensive review. *Ann Pediatr Cardiol*. 2023;16(3):201-209. https://doi.org/10.4103/apc.apc_201_23.
Singh A, et al. Long-term outcomes after transcatheter closure of ventricular septal defects in pediatric patients. *Heliyon*. 2025; e42157. https://doi.org/10.1016/j.heliyon.2025.e42157.
Patel N, et al. Complications following transcatheter ventricular septal defect closure: incidence and management. *Pediatr Cardiol*. 2025. https://doi.org/10.1007/s00246-025-03857-x.
Lee S, et al. Predictors of adverse outcomes after device closure of ventricular septal defects: insights from a large registry. *J Am Heart Assoc*. 2025;14(4):e039443. https://doi.org/10.1161/JAHA.124.039443.
Ece I, et al. Transcatheter ventricular septal defect closure with LifetechTM Konar-MF occluder in infants under ten kilograms with only using venous access. *Pediatr Cardiol*. 2023. https://doi.org/10.1007/s0 0246-023-03350-3.
Dilawar M, et al. Transcatheter closure of perimembranous ventricular septal defect using Amplatzer duct occluder: Immediate and mid-term results. *J Interv Cardiol*. 2008;21(3):273-278.
Tan JL, et al. Transcatheter closure of perimembranous ventricular septal defect using Amplatzer duct occluder. *Catheter Cardiovasc Interv*. 2005;66(3):436-441.
Ece I, et al. Transcatheter closure of ventricular septal defects by exclusive venous access in infants under 10 kg. *medRxiv*. 2024. https://doi.org/10.1101/2024.05.28.24308078v1.
Annals of Saudi Medicine. Transcatheter device closure of ventricular septal defects in children: a retrospective study at a single cardiac center. 2020;40(5):396-402.
Open Access Journals. Transcatheter Closure of Ventricular Septal Defects (VSD): preliminary results in children weighing 10 kg or less. 2024.
Research Square. Transcatheter ventricular septal defect closure with LifetechTM Konar-MF occluder in infants under ten kilograms with only using venous access. 2023.
MedRxiv. Transcatheter closure of ventricular septal defects by exclusive venous access in infants under 10 kg. 2024.
PubMed. Transcatheter Ventricular Septal Defect Closure with Lifetech Konar-MF device in infants under 10 kg using only venous route. 2024.
Sciencedirect. Transcatheter Closure of Atrial and Ventricular Septal Defects. *J Am Coll Cardiol*. 2023;81(6):551-563.
IJConline. Transcatheter Closure for Ventricular Septal Defect (VSD). 2024.
Yusubov A, Inagamov S, Hoon K. Transcatheter closure of perimembranous ventricular septal defect using single arterial access. Eurasian J Med Nat Sci. 2024;4(5):135–141.
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