Jild 4 № 1 (2026): Yanvar-Mart
54-59
2026-03-30
Ochiq kirish

Siydik pufagi ekstrofiyasi bo‘lgan bolalarda siydik pufagi bo‘ynini rekonstruksiya qilishda autologik trombotsitlarga boy fibrin membranasi yordamida erta yara asoratlarining oldini olish

Z.B. Abdullaev
S.T. Agzamxodjaev
T.G. Aliyev
https://doi.org/10.63417/

Qabul qilingan: 2026-10-05

Nashr etilgan: 2026-03-30

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Annotatsiya

Dolzarbligi. Siydik pufagi ekstrofiyasi bo'lgan bolalarda siydik pufagi bo'ynini rekonstruksiya qilish erta yara asoratlari xavfi bilan kechadi; autologik trombotsitlarga boy fibrin (PRF) membranasi chok chizig'ini qo'shimcha biologik qoplash imkonini berishi mumkin.


Maqsad. Siydik pufagi bo'yni rekonstruksiya qilingan sohani autologik PRF membranasi bilan qo'shimcha qoplashning erta yara asoratlarini oldini olishdagi samaradorligini baholash.


Materiallar va usullar. Milliy bolalar tibbiyot markazida operatsiya qilingan siydik pufagi ekstrofiyasi bo'lgan 86 nafar bola kuzatildi. 15 nafar bolada bolaning o'z qonidan 5-10 ml olinib, 3000 ayl/min tezlikda 13-15 daqiqa sentrifugalash orqali tayyorlangan PRF membranasi siydik pufagi bo'yni chok chizig'i ustiga joylashtirildi; 69 nafar bolada bunday qoplama qo'llanilmadi. Fisherning aniq testi, Spearman korrelyatsiyasi, logistik regressiya va ROC-tahlil qo'llanildi.


Natijalar. PRF qoplamasi qo'llanilgan bolalarda asoratlar 13,3% hollarda, qoplamasiz guruhda esa 43,5% hollarda kuzatildi (p = 0,039; OR 0,20; 95% CI 0,06-1,00). Membrana yagona statistik ahamiyatli himoya omili bo'ldi (rho = -0,24; p = 0,029); qov suyaklari diastazi, siydik pufagi hajmi va yosh prognostik ahamiyat ko'rsatmadi (AUC <= 0,56). Model AUC ko'rsatkichi 0,66 ni tashkil etdi.

Kalit so‘zlar

Adabiyotlar ro'yxati

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Mualliflar haqida

Z.B. Abdullaev
info@hnchmc.uz
S.T. Agzamxodjaev
info@hnchmc.uz
T.G. Aliyev
info@hnchmc.uz

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Siydik pufagi ekstrofiyasi bo‘lgan bolalarda siydik pufagi bo‘ynini rekonstruksiya qilishda autologik trombotsitlarga boy fibrin membranasi yordamida erta yara asoratlarining oldini olish. (2026). Bolalar Milliy Tibbiyot Markazining Axborotnomasi, 4(1), 54-59. https://doi.org/10.63417/

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